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"Event-Related Potential Correlates of
Interhemispheric Interaction in Adults with Attention Deficit Hyperactivity
Disorder "
by Rebecca Von Der Heide
Neuroanatomical research studies have provided evidence of differences in brain
structure that may be associated with attention-deficit disorder (ADHD). One
specific structure for which deficits in size, volume and shape have been found
is the corpus callosum, a structure that connects the right and left hemispheres
of the brain allowing them to communicate with one another. This communication
between the hemispheres can be referred to as interhemispheric interaction.
Despite structural evidence from neuroanatomical research studies of ADHD- related
differences of the corpus callosum, there has only been one study that has examined
the impact of these structural differences on interhemispheric communication
in an ADHD population. Not surprisingly, this lone study tested a group of young
boys with ADHD, the most prevalent and historically researched experimental
group with this disorder. While differences in interhemispheric communication
were found, the ability to generalize these results is limited by the need for
replication and by earlier evidence that the structure of the corpus callosum
is impacted by age and gender. The goal of the present study is to look at differences
in interhemispheric interaction in an experimental group comprised equally of
adult male and females with ADHD. Event-related potentials, which are waveforms
reflecting brain related-electrical activity in response to stimulation, will
be measured and analyzed to determine whether ADHD-related deficits in brain
structure found in earlier neuroanatomical studies are related to deficits in
interhemispehric communication. The primary novelty of this study is that it
will examine the impact of known gender and adult-related differences of the
corpus callosum on interhemispheric transfer in an ADHD population.